5F-PB-22 (5F-QUPIC or quinolin-8-yl 1-pentyfluoro-1H-indole-3-8-carboxylate) is a designer drug which acts as a cannabinoid agonist.The structure of 5F-PB-22 appears to have been designed with an understanding of structure–activity relationships within the indole class of cannabinoids
5F-PB-22
Buy 5F-BB22 Crystal is an analytical reference material that is structurally categorized as a synthetic cannabinoid (CB).
It is a full agonist of human CB1 and CB2 receptors (pEC50s = 8.55 and 7.97, respectively).1,2 5-fluoro PB-22 potently and dose-dependently induces hypothermia and reduces heart rate in rats, mimicking the in vivo effects of ?9-THC.1 This product is intended for research and forensic applications.
Pharmacology
5F-BB22 acts as a full agonist with a binding affinity of 1.94 nM at CB1 and 0.266 nM at CB2 cannabinoid receptors.
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Although they are synthetic, our cannabinoids have a close affinity with natural compounds that occur in the cannabis plant.
Not only do they release their effects in the same way (by interacting with cannabinoid receptors), but they are also associated with high selectivity and little to no toxicity.
Besides, our cannabinoids are proven to trigger the same nervous system responses, which is especially important for research in the area.
ADB-CHMINACA
ADB-FUBINACA
ADB-PINACA
ADBICA
APICA
APINACA
FUB-APINACA
MDMB-CHMICA
PX-3
Since the first appearance in the market, many new compounds have been synthetized in clandestine laboratories
through chemical alterations of the main structures, leading to different generations of SCs.
5F-PB22 (quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate) and BB-22 (quinolin-8-yl 1-
(cyclohexylmethyl)-1H-indole-3-carboxylate), also known as 5F-QUPIC and QUCHIC, are quinolinyl
ester indoles composed of an indole core substituted by a quinolinyl secondary structure through a carboxylate linker
